We attack the growing unmet medical needs in chronic inflammation
We face three major challenges that need concerted efforts of society and the R&D community as a whole. Given the multitude of the challenges, these efforts might be bigger than the Human Genome project or the fight against cancer.
Our main focus is on arthritic diseases like RA and Psoriasis and on COPD.
Chronic inflammation is the root cause of a complex disease group with high degree of co-morbidities. Those diseases take a huge toll on quality of life hundreds of millions of people.
Late detection and therapeutic solutions, dominated by complexity have a significant economic burden that can only be expressed in $trillions.
Our society faces a health challenge
Industry faces a discovery challenge
Most of inflammatory disease targets, dominated by protein-protein interactions are among the most difficult ones to drug.
Another challenge is that limited druggability of disease leads to “compromises” in target selection, potentially ignoring the targets most suitable for treatment. This includes the focus on one target rather than evaluating multi-target pathways.
Additionally, conventional methods limit the opportunities to discover and develop oral therapies leaving the field unnecessarily to complex and costly therapies like antibodies.
R&D faces a productivity and technology challenge
Besides tremendous technological progress, R&D in drug discovery and development is considered as slow and expensive. This low productivity paired with growing capital intensity leads to more than $1 billion on average to be invested to get one new drug to the market. In addition, the timeframe and costs for clinical trials needed to register new chemical entities (NCEs) has been extended in many cases to sometimes over 10 years.
- • Chronic Inflammatory diseases and their most challenging molecular targets.
- • Drug Discovery: Protein-protein interaction inhibitors, as well as ion channel inhibitors and designed small molecules to replace therapeutic proteins.
- • Herbal Medicine: Completely scientifically developed herbal products for preventative medicines.
Sanoosa Pty. Ltd.
Level 30, 35 Collins Street
Melbourne Vic 3000