Sanoosa’s Compound Libraries & Non-trivial Chemistry
We have compiled a diverse virtual library of >250k compounds from a large >7 million compounds library that we use to discover novel scaffolds for our or our partners’ targets.
In addition, we have compiled a virtual library of 20,000 naturally occurring small active molecules. With our unique in-silico discovery platform we also screen this library against our drug targets of interest. Furthermore, we are complementing our libraries with carbon sp3-rich compounds. Restricted rotation and conformations of molecules allows for specific design for unconventional binding sites (incl. surfaces) and protein-protein interactions. This non-trivial chemistry and the related novel substitution patterns open up new chemical space/bioactivities.
Designing and synthesising amended naturally occurring compounds as well as sp3-rich compounds is part of Sanoosa’s capability portfolio.